Differential effects of lesions of the dorsomedial and dorsolateral caudate-putamen on reaction time performance in rats.
نویسندگان
چکیده
In order to investigate the role of the dorsomedial and dorsolateral caudate-putamen (CPu) in movement initiation of rats, we examined the effects of quinolinic acid lesions (30 nmol in 1 microliter) in these striatal subregions in a simple reaction time task. Results show that lesions of the dorsomedial, but not of the dorsolateral CPu increased reaction times. These findings provide further evidence for a functional heterogenity of the CPu and demonstrate an involvement of the dorsomedial CPu in processes related to rapid initiation of responses.
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ورودعنوان ژورنال:
- Behavioural brain research
دوره 60 2 شماره
صفحات -
تاریخ انتشار 1994